Analysis Design
Lipidomic analysis (metabolomic analysis in general) is fundamentally different from its elder cousins, Genomic or Proteomic analyses. Both Genomic and Proteomic analyses are sequence determinations of repeating monomers; four nucleotide bases in the Genome and 20 amino acids in the Proteome. Lipidomics on the other hand involves the analysis of about 150,000 structurally diverse compounds that span a mass range of about 1,500 Da with few repeating units, if any. This complexity necessitates a ‘divide and conquer’ approach to manage the analysis. Even when the Lipidome is divided into classes of compounds, structural diversity within each class demands multiple methods to handle the analytical requirements. The following limited classification helps you to design the analysis relevant to your study. For the most comprehensive classification of the Lipidome, please visit LipidMaps consortium website.
Lipid classification to assist analysis design
- Fatty Acyl lipids
- Glycerolipids
- Glycerophospholipids
- Lyso-Glycerophospholipids
- Sphingolipids
- Sterol Lipids
- Isoprenoids
- Polyketides
- Other
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Please review the list of Frequently Asked Questions to help you guide your analytical needs.